Viagra
Viagra

Viagra

Warnings

Viagra can interact with some medicines that may cause side effects or even death. Inform your doctor about any medications you are currently taking, including riociuguat and nitrates.

If you’re taking Viagra 100 mg for chest pain, heart problems. Or other reasons, such as nitroglycerin and isosorbide mononitrate. Nitroglycerin, and/or some recreational drugs like poppers. Sildenafil taken with a nitrate medication can lead to a rapid and severe drop in blood pressure.

If your pain persists or your erection lasts more than four hours, contact your doctor immediately. Priapism (a prolonged erection) can cause damage to the penis. If you experience sudden vision loss, stop using Viagra and seek emergency medical attention.

Before you take this medicine

Viagra should not be used if you have an allergy to sildenafil.

If you are taking nitrates.

If you’re taking Viagra while also taking a nitrate medication for chest pain or heart disease. These include nitroglycerin and isosorbide dinitrate. Some recreational drugs, such as amyl-nitrate and nitrite (“poppers”), contain nitrates. Sildenafil taken with a nitrate medication can lead to a rapid and severe drop in blood pressure.

Heart disease, heart rhythm problems, and coronary artery disease are all possible.

A heart attack, stroke or congestive cardiac failure.

  • High or low blood pressure
  • Liver or kidney disease
  • A bleeding disorder like hemophilia
  • a stomach ulcer;

Retinitis pigmentosa is an inherited condition that affects the eyes. Which can reduce blood flow to the optic nerve. This happened in a small percentage of sildenafil users, many of whom had diabetes, heart disease, high blood pressure, or other eye problems. It also occurred in smokers and those over 50.

It is unclear if sildenafil is actually causing vision loss. Without medical advice, do not give this medicine to anyone younger than 18 years.

What should I do to take Viagra?

Follow the instructions on your prescription label. Follow the instructions on your prescription label. You cannot induce erection by simply taking a pill. Follow the instructions of your doctor. If you feel dizzy, nauseated or have pain in your neck, jaw, chest, neck or arms while sexual activity is ongoing, call your doctor immediately. Sildenafil could cause serious side effects.

Overdose

Studies with healthy volunteers showed that adverse reactions to single doses of 800 mg were comparable to those experienced at lower doses, but the incidence rates and severity were higher.

CONTRAINDICATIONS

Nitrates

Its known effects on the nitric dioxide/cGMP. Hypotensive Effects of nitrates and their administration to patients.

Hypersensitivity Reactions

.Concomitant Guanylate (GC) Stimulators

PDE5 inhibitors such as VIAGRA may increase the hypotensive effect of GC stimulators.

What happens if I miss a dose of medication?

What happens if I take too much?

Call the Poison Help Line at 1-800-222-1222 if you need immediate medical attention.

What to Avoid

Sildenafil may react with grapefruit juice and grapefruit juice, causing unwanted side effects. Do not consume grapefruit juice or other grapefruit products when taking sildenafil.

You should not use any other medications to treat impotence such as yohimbine or alprostadil without consulting your doctor.

Viagra side effects

If you are ill, get emergency medical attention Signs of an allergic reaction to Viagra Hives; difficulty breathing; swelling of the lips, throat, and lips.

If you are experiencing side effects, stop taking Viagra 100 mg . Get emergency medical attention.

Heart attack symptoms include chest pain, pressure, headaches, nausea, and sweating.

  • vision changes or sudden vision loss; or
  • Erection is uncomfortable or lasts more than four hours. Prolonged erection can cause damage to the penis.
  • Ringing in the ears or sudden loss of hearing;
  • An irregular heartbeat
  • Breathing difficulty
  • seizure (convulsions); or
  • A lightheaded feeling that you feel like you are going to pass out.
  • Some common side effects of Viagra include:
  • Flushing (warmth, redness or tingling sensation);
  • headache, dizziness;
  • Atypical vision: blurred vision, color vision changes.
  • Nosebleeds, runny or stuffy nose
  • sleep problems (insomnia);
  • muscle pain, back pain;

Symptoms of upset stomach

These are not all side effects. Other side effects may also occur. For medical advice regarding side effects, consult your doctor. Side effects can be reported to FDA at 1-800-FDA-1088.

What other drugs can affect Viagra?

Inform your doctor about any new or discontinued medications, and especially:

  • High blood pressure drugs or prostate disorders;
  • Antibiotic Clarithromycin or erythromycin are available;
  • antifungal medicine – ketoconazole or itraconazole
  • Medicine to treat HIV/AIDS – atazanavir, indinavir, ritonavir, or saquinavir;
  • Nitrates;

Treatments for pulmonary arterial hypertension.

This is not a complete list. Sildenafil may interact with prescription and over-the counter medicines, vitamins, herbal products, and other drugs. This medication guide does not list all possible interactions.

VIAGRA’s effects on erectile response

With patients suffering from either organic or psychogenic Erectile Dysfunction. The results of sexual stimulation showed that it improved erections. This was based on an objective measurement of hardness (Registan(r),) and the duration of erections after VIAGRA administration. Registan (r) showed that the erectile response to sildenafil increased with increasing plasma concentrations and sildenafil dosage. One study examined the time course of the effect. It showed a response for as long as 4 hours, but it was less than 2 hours.

VIAGRA’s effects on blood pressure

It caused a decrease in sitting blood pressure. The mean maximum decrease in systolic/diastolic bloodpressure was 8.3/5.3 mmHg. It was not different from placebo at 8 hours. VIAGRA 25 mg, 50 mg, and 100 mg had similar effects on blood pressure. The effects do not depend on plasma levels or dose. Patients who received concomitant nitrates had greater effects.

Pharmacokinetics

The mean absolute bioavailability for VIAGRA ranges from 41% to 2563%. Sildenafil’s pharmacokinetics are proportional to the recommended dosage range. The terminal half-lives of sildenafil as well as the metabolite are approximately 4 hours.

VIAGRA and Other Drugs: Effects

Sildenafil metabolism is mediated principally by CYP3A4 and CYP2C9, both major routes. Inhibitors of these enzymes may decrease sildenafil elimination, while inducers may increase sildenafil removal. Concomitant use erythromycin, strong CYP3A4 inhibitors (e.g., saquinavir), ketoconazole and itraconazole) is associated with higher plasma sildenafil levels.

Clinical Trials Experience

Clinical trials are conducted in a variety of conditions. Therefore, adverse reactions rates seen in clinical trials cannot be directly compared with rates seen in clinical trials for another drug. They may not reflect clinical practice rates.
During pre-marketing clinical trials, Viagra 100 mg was given to more than 3700 patients aged 19-87 during VIAGRA administration. More than 550 patients were treated more than one year.

The discontinuation rate for VIAGRA adverse reactions (2.5%) in placebo-controlled clinical trials was not significantly higher than placebo (2.3%). Fixed-dose studies showed that some adverse reactions were more common than others. These events were reported in less than 2% of patients who participated in controlled clinical trials. A causal relationship to VIAGRA remains unclear. The events reported include those that have a plausible relationship to drug use. Minor events and reports that are too vague to be meaningful are omitted.

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